On March 6, the Lady Eagles basketball team drove to Joplin, Missouri, to participate in this year's NCCAA DII Women's Basketball National Tournament. They came into the tournament as the number two seed.

On Wednesday, the Lady Eagles played their first game of the tournament. Their elite eight matchup was against the number seven seed, Trinity Bible College. The Lady Eagles dominated from the beginning, scoring over double the points that they allowed in the first quarter. During the second quarter, the Lady Eagles went on an 18–1 run. The Lady Eagles' strong play continued in the second half as they once again scored twice the number of points Trinity Bible did through the third and fourth quarter. The Lady Eagles defeated Trinity Bible College 81–31 to advance to the semifinal game.

Friday, the Lady Eagles faced the host school, Ozark Christian College, in the semifinal round. A slow start for the Lady Eagles left the score tied at thirteen at the end of the first quarter. The Lady Eagles continued to struggle to find their groove in the second quarter, and they went into the half down by two points. About halfway through the third quarter, the Lady Eagles found their spark and went on a 10–0 run. By the end of the third quarter, they were up 57–47. The Lady Eagles stayed strong in the fourth quarter and went on to win the game 89–72. This win allowed the Lady Eagles to advance to the National Championship game, an accomplishment that had previously only happened one time in program history.

Saturday evening, the Lady Eagles entered the championship game with a single goal—to win the first National Title in program history. They faced the Arlington Baptist University Patriots. The same team the Lady Eagles had faced in their last championship game appearance. It appeared that the Lady Eagles would have a slow start, as Arlington grabbed the first four points and then quickly went up 6–1. The Lady Eagles would not easily back down, and a 13–0 run quickly put them on top. They finished the quarter ahead by thirteen points. The Lady Eagles' dominant playing streak continued in the second quarter as they outscored the Patriots 25–4, ending the half with a 48–17 lead. However, Arlington would not give up easily. The Lady Eagles' shooting was challenged by strong defense from the Patriots. At the end of the third quarter the Lady Eagles' 31-point lead had been cut to 22 points. The Lady Eagles sat one quarter—10 minutes—away from their first National Title. Despite shooting struggles, they played aggressively on defense to keep the now on fire Arlington Baptist team from cutting the differential even farther. The Lady Eagles' lead dwindled down to 7 points, but a well-timed 3-pointer from Lauran Alvarez pushed the team back to a double-digit lead. A few minutes later, the game clock expired, with the final score 85–74, in favor of the Lady Eagles.

On their nineth-straight trip to the National Tournament, the Lady Eagles accomplished what they had never done before—won a National Title.

Two players were named to the All-Tournament Team, Leah Phelps and Lauran Alvarez. Lauran Alvarez was also named the Tournament's Most Outstanding Player.